HLA-IMMUNOGENETICS IN MULTIPLE SCLEROSIS : ON CLINICAL APPLICATIONS AND PERSONALIZED THERAPEUTICS Εκτύπωση

Neurologist-Neuroimmunologist, Assistant Professor of Neurology

Medical School of Athens National and Kapodistrian University (NKUOA), Athens, Greece

Multiple Sclerosis (MS) is a multifactorial disease of the Central Nervous System, with a neuroinflammatory and a neurodegenerative component, from its initiation and further on. Many factors have been described to play a role in the initiation and clinical course of the disease and in the response to medication. These factors include age at onset, gender, viral infections, Human Leucocyte Antigen (HLA)-genotype, non-HLA genes, Vitamin D levels, Body-Mass-Index(BMI) and smoking...

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